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temple University Hospital



(Philadelphia, PA) – Temple University Hospital is testing whether implanting miniature coils in the airways of diseased lungs can improve breathing, activity levels and quality of life for emphysema patients.


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The coils work by compressing damaged tissue, which allows the healthier parts of the lung to function more efficiently and make breathing easier. The coils are made of Nitinol, a metal commonly used in medical implants, and offer a minimally invasive alternative to lung volume reduction surgery.


Temple is testing the RePneu® Lung Volume Reduction Coils as part of the Lung Volume Reduction Coil Treatment in Patients with Emphysema (RENEW) Study, which is being conducted by Californiabased PneumRx, the company that makes the coils. European studies have shown that patients treated with the coils have an improved quality of life, better ability to exercise and reduced breathlessness.

“The RePneu coils are delivered through a bronchoscope in a short, nonsurgical procedure that is performed under conscious sedation or general anesthesia,” says Gerard Criner, MD, Chair of the Department of Medicine at Temple University School of Medicine and lead investigator of the trial at Temple. “A typical procedure takes approximately 30 minutes and involves the implantation of about 10 coils.”


“Our involvement in the RENEW study means that we can give emphysema patients an option that most hospitals don’t offer,” continues Dr. Criner, who is also Director of the nationallyranked Temple Lung Center, one of the nation’s leaders in the diagnosis, treatment and research of patients with complex lung problems. The RePneu coils are preformed into a coil shape, but they are delivered to the lung in a straight configuration. When the coils are deployed into the lung, they recover to their original shape, gathering and compressing diseased tissue and allowing the healthy tissue to function better. The coils are a permanent implant. To watch a video of the procedure, visit


This research study is a randomized controlled study. After a prescreening process, those who meet the clinical criteria for study participation are randomized to either standardofcare (the control group) or undergo the coil procedure. After the 12month study is complete, those in the control group may have a chance to receive the coil. This will be decided after a medical committee and the FDA reviews the study safety data and allows the study to proceed.

Temple is currently prescreening patients for the RENEW study. Interested patients may call Kathy McLeer, RN, research program manager, at 2157074821 for more information.


Editor’s Note: Dr. Criner has no financial interest in PneumRx, manufacturer of the RePneu® Lung Volume Reduction Coil.


About Temple Health

Temple Health refers to the health, education and research activities carried out by the affiliates of Temple University Health System and by Temple University School of Medicine.


Temple University Health System (TUHS) is a $1.4 billion academic health system dedicated to providing access to quality patient care and supporting excellence in medical education and research. The Health System consists of Temple University Hospital (TUH), ranked among the “Best Hospitals” in the region by U.S. News & World Report; TUHEpiscopal Campus; TUHNortheastern Campus; Fox Chase Cancer Center, an NCIdesignated comprehensive cancer center; Jeanes Hospital, a communitybased hospital offering medical, surgical and emergency services; Temple Transport Team, a ground and airambulance company; and Temple Physicians, Inc., a network of communitybased specialty and primarycare physician practices. TUHS is affiliated with Temple University School of Medicine.


Temple University School of Medicine (TUSM), established in 1901, is one of the nation’s leading medical schools. Each year, the School of Medicine educates approximately 720 medical students and 140 graduate students. Based on its level of funding from the National Institutes of Health, Temple University School of Medicine is the second highest ranked medical school in Philadelphia and the thirdhighest in the Commonwealth of Pennsylvania. According to U.S. News & World Report, TUSM is among the top 10 most appliedto medical schools in the nation.


The copyrights for these articles are owned by the Hellenic News of America. They may not be redistributed without the permission of the owner. The opinions expressed by our authors do not necessarily reflect the opinions of the Hellenic News of America and its representatives.